Puck drop 7:40 PM ETWed, Oct 21 · 7:40 PM ET · Scripps Sports, ESPN+ (US); Prime Video (Canada)

Panthers vs SenatorsPrediction, Picks & Odds

Panthers

@

Senators

Moneyline
-108
-106
Puck line
+1.5 -286
-1.5 +231
Total 5.5
O-110
U-106

Odds checked 7:05 PM ET · 21+ · Bet responsibly

The SportsHub verdictUpdated 8:04 PM ET

Our pick: Panthers ML (-110)

Panthers 62%38% Senators
Fair line
Panthers -163
Edge
+11.8 pts

11 verified experts bet this game.

+7

The top-ranked NHL experts agree 2 of 4 on one side.

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Expert picks for this game

11 verified handicappers have a pick on Panthers vs Senators. Records are NHL, last 30 days.

  • Keylor Santos

    28-17 · 62.2%

    +$885
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    Profit
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  • Pro Picks - Mike

    22-16 · 57.9%

    +$436
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  • Kyle Parker

    11-10 · 52.4%

    +$140
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  • Frankie the Fan

    2-1 · 66.7%

    +$107
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    MoneylineLocked Moneyline pickUnlock
    TotalLocked Total pickUnlock
  • Sean Murphy

    2-1 · 66.7%

    +$94
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    Free pick · MoneylineFree with an account

6 more experts picked this game

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Where the experts landed

How many of the 11 handicappers on this game picked each market, and whether the best of them agree.

All experts

7 of 11 picked the moneyline

Top 25% NHL experts by profit, last 30 days · 4 picks

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2 of 4 agree on one sideSee which

Small samples are noisy: consensus is a signal, not a pick.

Our prediction

Free, every game: the model's numbers, checked against the market.

62%Panthers win

Our pick · Medium confidence

Our pick: Panthers ML (-110)

Model fair line
Panthers -163
Market
Panthers -108
Edge
+11.8 pts

Key factors

  • Shot volumeEdge PanthersFlorida outshoots opponents 29.3 to 24.0 per game (5th in shots allowed). Ottawa takes 23.1 shots a game (29th) and allows 26.2.
  • Power playEdge PanthersFlorida's power play runs at 20.9% (13th) against Ottawa's 12.8% (28th). The penalty kills are nearly even at 80.6% and 79.4%.
  • GoaltendingEdge SenatorsWith Markstrom on IR, Akira Schmid (2-1-1, 3.25 GAA, .878) is expected to start. Linus Ullmark is 6-1-0 with a 1.33 GAA and .945 for Ottawa.
  • InjuriesEvenFlorida is without Barkov, Marchand and Markstrom. Ottawa loses Chabot for one to two weeks but gets Jake Sanderson back after eight games out.

Panthers vs Senators odds

Current prices, and how each market moved since it opened at the same book.

MarketPanthersSenators
MoneylinePanthers -105 → -108-108-106
Puck lineFlat since open+1.5 -286-1.5 +231
Total 5.5Flat since openOver -110Under -106

Analysis

Panthers vs Senators Prediction, Picks & Odds (Oct. 21, 2026)

By SportsHub Model · Edited by Kyle Parker

The 20-second version

  • Pick: Panthers moneyline (-110), medium confidence. The model gives Florida 62% against a coin-flip price.
  • Florida takes 29.3 shots a game and allows 24.0; Ottawa generates only 23.1 shots a game, 29th in the NHL.
  • Power play: Florida converts 20.9% (13th), Ottawa 12.8% (28th).
  • The swing is in goal: Akira Schmid (.878) is expected for Florida, while Linus Ullmark is at .945 for Ottawa.
Panthers vs Senators prediction, picks and odds for Oct. 21, 2026: SportsHub picks the Panthers moneyline at -110

The Florida Panthers (5-2-2) visit the Ottawa Senators (6-3-0) on Wednesday, Oct. 21 at 7:30 p.m. ET at Canadian Tire Centre, on Scripps Sports and ESPN+ in the US. The moneyline is a coin flip, -106 to -112 on either side, and that's the tension: Florida owns the shot share and the power play, Ottawa owns the hottest goalie in the matchup. Brady Tkachuk also makes his first trip back to Ottawa. Our pick: Panthers moneyline (-110), medium confidence.

How these teams got here

Florida has won three straight, capped by an 8-3 rout of Seattle on Saturday. The Panthers score 3.33 goals per game (10th) and allow 2.78 (11th), and they are 3-1-2 on the road. They've done it without Aleksander Barkov and Brad Marchand, which says a lot about the depth Paul Maurice still has.

Ottawa is 6-3-0 and 3-1-0 at home, but it is coming off a 3-1 loss to Philadelphia on Saturday, a game in which captain Thomas Chabot left after two periods. The Senators' record is built on defense: they allow just 2.56 goals per game (8th) while scoring only 2.44 (24th).

Both teams have had three days off. The schedule spot belongs to Ottawa, though: Florida plays in Pittsburgh on Thursday, which is why the Panthers recalled goalie Cooper Black from Charlotte.

Shot volume vs. a hot goalie

This game comes down to whether Florida's volume can beat Ottawa's goaltending.

The gap in play is wide. Florida takes 29.3 shots per game (11th) and allows 24.0 (5th). Ottawa gets just 23.1 shots per game (29th) and gives up 26.2 (14th). On the power play, the Panthers convert 20.9% (13th) against the Senators' 12.8% (28th). The penalty kills are a wash at 80.6% and 79.4%.

The Tkachuk brothers drive Florida. Matthew Tkachuk leads the team with 14 points (3 G, 11 A), and Brady Tkachuk has 6 goals and a team-high 32 shots in his first season in Florida, after eight years and 463 points in Ottawa. For the Senators, Tim Stützle leads with 12 points (5 G, 7 A).

In goal, the edge flips. Jacob Markstrom is out, and Akira Schmid is expected to start for Florida, per NHL.com: he is 2-1-1 with a 3.25 GAA and .878 save percentage. Ottawa had not named its starter as of Tuesday night. Linus Ullmark has been outstanding at 6-1-0, 1.33 GAA, .945, while Samuel Ersson is 0-2-0 with a .829.

Who's missing

Florida is thin down the middle and in net. Barkov and Marchand are on injured reserve, and Markstrom (3-1-1, 2.21 GAA, .897) went on IR after getting hurt in practice and is expected to miss one to two weeks. That puts the crease in Schmid's hands with Black as the backup.

Ottawa loses its top minutes on the back end. Chabot is out one to two weeks with an upper-body injury, per coach Travis Green. The offset is Jake Sanderson, who is expected to return after missing eight games. William Eklund remains on IR.

Prediction: Panthers moneyline

Panthers moneyline (-110), medium confidence. The reasons:

  1. Price vs. probability. The model gives Florida 62% to win. At -106 to -112, the market implies roughly a coin flip.
  2. Shot volume. Florida outshoots its opponents 29.3 to 24.0 a night. Ottawa generates only 23.1 shots a game, 29th in the league.
  3. Special teams. A 20.9% power play against a 12.8% one is a real gap in a game expected to be tight.
  4. Ottawa's offense. At 2.44 goals per game, the Senators have little margin if Ullmark is merely good instead of great.
  5. The blue line. Chabot's absence costs Ottawa its top-pair minutes, even with Sanderson back.

The risk: goaltending. Ullmark's .945 against Schmid's .878 is the single biggest swing in this matchup. If Ullmark stays at that level, Ottawa can win a low-scoring game.

The total: most licensed books sit at 5.5 with the over at -120 to -127, with a couple at 6. Schmid's numbers push it up; Ottawa's 2.44 goals per game pull it down. No play on the total.

Tale of the tape

Season to date. The better side of each stat is highlighted; league rank in brackets.

PanthersSenators
  • 5-2-2 Record 6-3-0
  • 3.33 (10th)Goals per game(24th) 2.44
  • 2.78 (11th)Goals allowed per game(8th) 2.56
  • 29.3 (11th)Shots per game(29th) 23.1
  • 24.0 (5th)Shots allowed per game(14th) 26.2
  • 20.9% (13th)Power play %(28th) 12.8%
  • 80.6% (16th)Penalty kill %(17th) 79.4%
  • 3-1-2 road Road / home record 3-1-0 home

Panthers injuries

  • Aleksander BarkovCIR
  • Brad MarchandLWIR
  • Jacob MarkstromGIR

Senators injuries

  • Thomas ChabotDOut
  • William EklundLWIR

As of Oct 20, 8:05 PM ET

Panthers vs Senators FAQ

What channel is Panthers vs Senators on?

Panthers vs Senators airs on Scripps Sports and streams on ESPN+ in the US. In Canada, the game is on Prime Video.

Who is starting in goal for Panthers vs Senators?

Akira Schmid is expected to start for the Panthers with Jacob Markstrom on injured reserve, per NHL.com. The Senators had not named a starter as of Tuesday night; Linus Ullmark is 6-1-0 with a .945 save percentage and Samuel Ersson is the other option.

What is SportsHub's pick for Panthers vs Senators?

SportsHub's pick is the Panthers moneyline at -110, with medium confidence. Florida's edge in shot volume and on the power play outweighs the coin-flip price, though Ullmark's form in the Senators' net is the main risk.

Is Brady Tkachuk playing in Ottawa against the Senators?

Yes. Brady Tkachuk returns to Ottawa with the Panthers after eight seasons and 463 points with the Senators. He has 6 goals and 10 points in nine games for Florida this season.

Who is injured for the Panthers and Senators?

The Panthers are without Aleksander Barkov, Brad Marchand and goalie Jacob Markstrom, all on injured reserve. The Senators are without captain Thomas Chabot (out one to two weeks) and William Eklund, while Jake Sanderson is expected back.

Who is favored to win Florida Panthers vs Ottawa Senators?

Florida Panthers are favored over Ottawa Senators based on the latest moneyline (Panthers -108, Senators -106).

What is the point spread for Florida Panthers vs Ottawa Senators?

Panthers 1.50, Senators -1.50. Spread reflects the projected margin between the two teams.

What is the over/under for Florida Panthers vs Ottawa Senators?

The total (over/under) is 5.50. Over 5.50 or under 5.50 wins respectively.

When is Florida Panthers vs Ottawa Senators?

Florida Panthers vs Ottawa Senators is scheduled for Wed, Oct 21 at 7:40 PM ET.

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