Kickoff 4:25 PM ETSun, Nov 15 · 4:25 PM ET · Fox

Cowboys vs 49ersPrediction, Picks & Odds

Cowboys

4-5-0
vs

49ers

7-1-0
Moneyline
+175
-208
Spread
+4 -110
-4 -110
Total 56
O-110
U-110

Odds checked 10:54 AM ET · 21+ · Bet responsibly

The SportsHub verdictUpdated 5:21 PM ET

Our pick: 49ers ML (-213)

Cowboys 25%75% 49ers
Fair line
49ers -300
Edge
+10.0 pts

9 verified experts bet this game.

+5

The top-ranked NFL experts agree 2 of 3 on one side.

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Expert picks for this game

9 verified handicappers have a pick on Cowboys vs 49ers. Records are NFL, last 30 days.

  • Sean Kuchman

    19-13 · 59.4%

    +$535
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  • Nolan Brooks

    3-0 · 100.0%

    +$300
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  • Pro Picks - Mike

    4-1 · 80.0%

    +$290
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  • Kurt Binck

    4-4 · 50.0%

    -$32
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  • Jack Jones

    0-1 · 0.0%

    -$110
    Record
    Win %
    Profit
    Free pick · SpreadFree with an account

4 more experts picked this game

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Where the experts landed

How many of the 9 handicappers on this game picked each market, and whether the best of them agree.

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8 of 9 picked the spread

Top 25% NFL experts by profit, last 30 days · 3 picks

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2 of 3 agree on one sideSee which

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Our prediction

Free, every game: the model's numbers, checked against the market.

75%49ers win

Our pick · High confidence

Our pick: 49ers ML (-213)

Model fair line
49ers -300
Market
49ers -208
Edge
+10.0 pts

Key factors

  • Scoring marginEdge 49ersSan Francisco has outscored opponents 235-156 (+79) in eight games. Dallas is 246-236 (+10) in nine.
  • Third downsEdge 49ersThe 49ers convert 51.7% of third downs (2nd in the NFL). Dallas allows 48.3%, the worst rate in the league per the AP.
  • Dallas run game vs. SF frontEdge 49ersDallas has averaged 159 rushing yards over its last three games, but San Francisco is the only team that hasn't allowed a 20-yard run this season.
  • 49ers' left tackle and receiversEdge CowboysTrent Williams is questionable after two missed practices and Mike Evans is out. Deebo Samuel returns with no designation.
  • Dallas secondaryEdge 49ersSafety P.J. Locke is out, Juanyeh Thomas is doubtful and corners Daron Bland and Joey Porter are questionable.

Cowboys vs 49ers odds

Current prices, and how each market moved since it opened at the same book.

MarketCowboys49ers
MoneylineCowboys -120 → +175+175-208
SpreadCowboys -1.5 → +4+4 -110-4 -110
Total 56Opened 52.5 → 56Over -110Under -110

Analysis

Cowboys vs 49ers Prediction, Picks & Odds (Week 10)

By SportsHub Model · Edited by Kyle Parker

The 20-second version

  • Pick: 49ers moneyline at -213. The model has San Francisco around 74%, above the roughly 68% the price implies.
  • San Francisco is +79 in scoring margin through eight games; Dallas is +10 through nine and 1-3 at home.
  • Trent Williams (shoulder) is questionable after missing Thursday and Friday practice. He is the swing factor.
  • The line sits at 49ers -3.5 to -4 (down from -4.5 earlier in the week) with a 55.5 to 56 total.
Cowboys vs 49ers Week 10 prediction card: 49ers moneyline at -213

The San Francisco 49ers (7-1) visit the Dallas Cowboys (4-5) at AT&T Stadium on Sunday at 4:25 p.m. ET on Fox, laying 3.5 to 4 points with a total of 55.5 to 56. San Francisco has beaten Dallas four straight times and owns a share of the NFL's best record, but it arrives without Mike Evans and with left tackle Trent Williams questionable. Our call: 49ers moneyline (-213). The model has them clearly above the price.

How these teams got here

San Francisco is 7-1 and has outscored opponents 235-156, a margin of nearly 10 points per game. The only loss came 29-20 at Atlanta on Oct. 25. After a bye, the Niners came back with a 38-17 rout of the Raiders, holding Las Vegas to 24 rushing yards, their lowest allowed in 11 years per the AP.

Dallas is 4-5 under Brian Schottenheimer, with 246 points scored and 236 allowed. The Cowboys beat the Colts 27-23 last week, one week after a 33-30 overtime loss to Arizona at home. Home has been the problem: Dallas is 1-3 at AT&T Stadium and 3-2 on the road. The Cowboys haven't won two in a row since a three-game streak last November.

Dallas' ground game vs. the 49ers' front

The Cowboys found something on the ground. They are averaging 159 rushing yards per game over their last three, about 100 more than the three before that, per the AP. Javonte Williams has 629 yards and 9 touchdowns. The problem is San Francisco is the only team that hasn't allowed a run of 20 or more yards this season, and Fred Warner (77 tackles, five forced fumbles) runs that defense.

Through the air, Dak Prescott has 2,381 yards, 16 TDs and 5 INTs, and CeeDee Lamb has 70 catches for 904 yards. George Pickens practiced fully Friday and carries no designation.

On the other side, Brock Purdy is efficient: 1,980 yards, 17 TDs and 5 INTs on 163-of-236 passing. San Francisco converts 51.7% of its third downs, second-best in the league, and gets to face the worst third-down defense in the NFL (Dallas allows 48.3%, per the AP). Christian McCaffrey has 9 rushing touchdowns, and Quinnen Williams (league-high 14 tackles for loss) is the Dallas defender who can wreck the script.

Who's in, who's out

The Niners' receiving room is thin. Mike Evans (Achilles) is out, but Deebo Samuel has no designation after missing three games, and Shanahan said he's clear to play. Keenan Allen, acquired from Indianapolis at the deadline, faces Dallas for the second straight week.

The bigger question is up front: Trent Williams (shoulder) is questionable after missing Thursday's and Friday's practices. "Sunday comes fast. But hopefully, that's enough time for him to be all right," Shanahan said. Cornerbacks Deommodore Lenoir and Renardo Green are also questionable but returned to practice Friday.

Dallas is down tight end Jake Ferguson and safety P.J. Locke (both out), and safety Juanyeh Thomas is doubtful. Corners Daron Bland and Joey Porter are questionable. That's a lot of uncertainty in a secondary that has to slow Purdy.

How the line has moved

San Francisco was -4.5 at several books earlier this week and now sits at -3.5 to -4. The moneyline runs -204 to -222. The total has gone the other way, from 53.5 to 54.5 around Nov. 8 to 55.5 to 56 now.

Prediction: 49ers moneyline (-213)

The pick is the 49ers to win outright at -213.

  1. Scoring margin. San Francisco is +79 through eight games; Dallas is +10 through nine.
  2. Third downs. The NFL's No. 2 third-down offense (51.7%) meets its worst third-down defense (48.3%).
  3. Model vs. market. The model puts San Francisco around 74%. The -213 price implies about 68%, and even the shortest licensed price (-204) needs 67.1%.
  4. Dallas at home. The Cowboys are 1-3 at AT&T Stadium.
  5. Absences. Dallas' secondary is short a starting safety and maybe two corners.

The risk: Williams. If he can't go, Purdy loses his blind-side protector against a Dallas front led by Quinnen Williams, and a passing game without Evans gets thinner. The ML is the cleaner route than laying 4 for that reason.

On the total: 55.5 to 56 asks a lot of a 49ers defense allowing 19.5 points per game, even with Dallas averaging 27.3. We have no play there.

Tale of the tape

Season to date. The better side of each stat is highlighted; league rank in brackets.

Cowboys49ers
  • 4-5 Record 7-1
  • 27.3 (6th)Points per game(3rd) 29.4
  • 26.2 Points allowed per game 19.5
  • 368.1 (11th)Total yards per game(7th) 382.8
  • 256.9 (6th)Passing yards per game(11th) 241.5
  • 103.6 (21st)Rushing yards per game(7th) 135.3
  • 45.3% (5th)Third-down conversion(2nd) 51.7%
  • -1 Turnover differential +1

Cowboys injuries

  • Jake FergusonTEOut
  • P.J. LockeSOut
  • Donovan EzeiruakuLBOut
  • Jonathan MingoWROut
  • Juanyeh ThomasSDoubtful
  • Daron BlandCBQuestionable
  • Joey PorterCBQuestionable

49ers injuries

  • Trent WilliamsTQuestionable
  • Mike EvansWROut
  • Deommodore LenoirCBQuestionable
  • Renardo GreenCBQuestionable
  • Dre GreenlawLBQuestionable
  • Upton StoutCBQuestionable

As of Nov 13, 5:18 PM ET

Cowboys vs 49ers FAQ

What channel is 49ers vs Cowboys on?

The 49ers vs Cowboys game airs on Fox on Sunday at 4:25 p.m. ET from AT&T Stadium in Arlington, Texas.

Is Trent Williams playing for the 49ers against the Cowboys?

Trent Williams is questionable for the 49ers against the Cowboys with a shoulder injury. He was added to the report Thursday and did not practice Thursday or Friday.

Is Deebo Samuel playing against the Cowboys?

Yes. Deebo Samuel carries no injury designation for 49ers vs Cowboys after missing three games with a hamstring injury, and Kyle Shanahan said he is clear to play. Mike Evans is out.

What is SportsHub's pick for 49ers vs Cowboys?

SportsHub's pick for 49ers vs Cowboys is the 49ers moneyline at -213. The model makes San Francisco about a 74% winner, above the roughly 68% the price implies.

How has the 49ers vs Cowboys line moved?

The 49ers were -4.5 at several books earlier this week and are now -3.5 to -4 against the Cowboys. The total has climbed from 53.5-54.5 to 55.5-56.

Who is favored to win Dallas Cowboys vs San Francisco 49ers?

San Francisco 49ers are favored over Dallas Cowboys based on the latest moneyline (Cowboys +175, 49ers -208).

What is the point spread for Dallas Cowboys vs San Francisco 49ers?

Cowboys 4.00, 49ers -4.00. Spread reflects the projected margin between the two teams.

What is the over/under for Dallas Cowboys vs San Francisco 49ers?

The total (over/under) is 56.00. Over 56.00 or under 56.00 wins respectively.

When is Dallas Cowboys vs San Francisco 49ers?

Dallas Cowboys vs San Francisco 49ers is scheduled for Sun, Nov 15 at 4:25 PM ET.

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