Arizona Cardinals vs Detroit LionsNFL Picks, Prediction & Odds β€’ Oct 11 β€’ 12:25 PM

Arizona Cardinals logo

Cardinals

21-45
Final
Detroit Lions logo

Lions

7Picks

Experts Betting This Game

7 experts have a pick on Cardinals vs Lions

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Will Rogers

Will Rogers

70% Win Rate
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Oskeim Sports

Oskeim Sports

70% Win Rate
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Keylor Santos

Keylor Santos

70% Win Rate
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Sports Central

Sports Central

30% Win Rate
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Jhon Walsh

Jhon Walsh

70% Win Rate
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Preview Β· 15s

Pre-Game Prediction

Arizona Cardinals logoCardinals32%
68%LionsDetroit Lions logo
Arizona Cardinals logo
Cardinals
VS
Detroit Lions logo
Lions
Confidence
Medium

We predict Detroit Lions to win

Key Factors

Betting Odds

Betting odds imply a 68% chance for Lions

Arizona Cardinals vs Detroit Lions NFL Preview – October 11, 2026

Prediction Result

βœ“ Correct
Cardinals
21
-
Lions
45
Our Pick
Lions
Actual Winner
Lions
7

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Frequently asked questions

Who is favored to win Arizona Cardinals vs Detroit Lions?

Detroit Lions are favored over Arizona Cardinals based on the latest moneyline (Cardinals +200, Lions -244).

What is the point spread for Arizona Cardinals vs Detroit Lions?

Cardinals 5.50, Lions -5.50. Spread reflects the projected margin between the two teams.

What is the over/under for Arizona Cardinals vs Detroit Lions?

The total (over/under) is 54.50. Over 54.50 or under 54.50 wins respectively.

When is Arizona Cardinals vs Detroit Lions?

Arizona Cardinals vs Detroit Lions is scheduled for Oct 11 at 12:25 PM ET.