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  1. Home/
  2. Picks/
  3. MLB/
  4. Guardians vs Orioles

Cleveland Guardians vs Baltimore OriolesMLB Picks, Prediction & Odds • Sep 7 • 01:36 PM

Cleveland Guardians logo

Guardians

0-0
Starting Now
Baltimore Orioles logo

Orioles

2Picks

Experts Betting This Game

2 experts have a pick on Guardians vs Orioles

View Expert Picks
Kyle Parker

Kyle Parker

30% Win Rate
Pick on this game
Premium pick +100Unlock
Keylor Santos

Keylor Santos

70% Win Rate
Pick on this game
Premium pick +100Unlock
Kyle Parker

Kyle Parker

30% Win Rate
Pick on this game
Premium pick +100Unlock
Keylor Santos

Keylor Santos

70% Win Rate
Pick on this game
Premium pick +100Unlock
Preview · 15s

Our Prediction

Free Pick
Cleveland Guardians logoGuardians57%
43%OriolesBaltimore Orioles logo
Cleveland Guardians logo
Guardians5
73-71American League #5
VS
Baltimore Orioles logo
Orioles
69-75American League #9
Confidence
Medium

We predict Cleveland Guardians to win 5-3

Key Factors

Betting Odds

Betting odds imply a 54% chance for Guardians

Season Record

Guardians is 73-71 this season

Standings Position

Guardians ranked #5 in standings

Head-to-Head

Guardians leads the recent series 3-1

Cleveland Guardians vs Baltimore Orioles MLB Preview – September 7, 2026

Cleveland Guardians vs Baltimore Orioles — MLB featured preview

Team Comparison

Cleveland Guardians logoGuardians
OriolesBaltimore Orioles logo
73-71
Record
69-75
50.7%
Win %
47.9%
#5
Ranking
#9

Head-to-Head

Last 4 meetings

Cleveland Guardians logo
3
Guardians
Baltimore Orioles logo
1
Orioles
75%
25%

Recent Matchups

Apr 16, 2026
4-2
Guardians
Apr 17, 2026
4-6
Orioles
Apr 18, 2026
4-2
Guardians
Apr 19, 2026
8-4
Guardians

H2H Averages (Last 3 Games)

4.0
3.3
Guardians AvgAvg ScoreOrioles Avg
2

Expert Picks Available

Professional handicappers have analyzed this game

Betting Odds

Cleveland Guardians logoGuardians
OriolesBaltimore Orioles logo
Spread
-1.50
+170
1.50
-196
Moneyline
-123
FAV
+112
Total (O/U 8.50)
Over
-105
Under
-115

Recent Matchups

4/19/20268 - 4

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Frequently asked questions

Who is favored to win Cleveland Guardians vs Baltimore Orioles?▾

Cleveland Guardians are favored over Baltimore Orioles based on the latest moneyline (Guardians -123, Orioles +112).

What is the point spread for Cleveland Guardians vs Baltimore Orioles?▾

Guardians -1.50, Orioles 1.50. Spread reflects the projected margin between the two teams.

What is the over/under for Cleveland Guardians vs Baltimore Orioles?▾

The total (over/under) is 8.50. Over 8.50 or under 8.50 wins respectively.

When is Cleveland Guardians vs Baltimore Orioles?▾

Cleveland Guardians vs Baltimore Orioles is scheduled for Sep 7 at 01:36 PM ET.

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See all MLB picks →
2

Expert Picks Available

Professional handicappers have analyzed this game

Betting Odds

Cleveland Guardians logoGuardians
OriolesBaltimore Orioles logo
Spread
-1.50
+170
1.50
-196
Moneyline
-123
FAV
+112
Total (O/U 8.50)
Over
-105
Under
-115
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SportsHub may earn a commission from sportsbook partners linked from this site. Picks and editorial content are produced independently of any partnership. Affiliate Disclosure

Please gamble responsibly. If you have a gambling problem, please visit ncpgambling.org