Sunday, June 21, 2026
Guardians57%
We predict Cleveland Guardians to win 6-3
Betting Odds
Betting odds imply a 54% chance for Guardians
Season Record
Guardians is 41-36 this season
Standings Position
Guardians ranked #3 in standings
Head-to-Head
Astros leads the recent series 3-2
GuardiansLast 5 meetings
Professional handicappers have analyzed this game
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Cleveland Guardians are favored over Houston Astros based on the latest moneyline (Guardians -125, Astros +113).
Guardians -1.50, Astros 1.50. Spread reflects the projected margin between the two teams.
The total (over/under) is 8.50. Over 8.50 or under 8.50 wins respectively.
Cleveland Guardians vs Houston Astros is scheduled for Jun 21 at 02:11 PM ET.