Premium Service Plays NCAA Week 4
The college football season is heating up, and Week 4 brings crucial matchups that could shake up the rankings. Now is the time to lock in expert service plays, top picks, and key betting opportunities. With teams battling for conference dominance and surprises unfolding, this week is a prime chance to capitalize. Whether you’re a seasoned bettor or just love the game, our expert insights will help you make the right calls!
2025 NCAA Football Week 4 Betting Preview and Predictions
As Week 4 rolls in, the 2025 college football season is heating up with conference matchups, revenge games, and trap spots that smart bettors can take advantage of. With three weeks of film and betting data available, this is where sharp handicappers really start separating from the pack.
SportsHub’s expert analysts have crunched the numbers and broken down the angles to help you make the smartest plays of the weekend. From against the spread picks to totals and prop bets, here’s what you need to know heading into Week 4.
Key Matchups to Watch in Week 4
- Michigan vs. Wisconsin – A Big Ten clash with serious playoff implications.
- Ole Miss vs. Alabama – Lane Kiffin returns to Tuscaloosa looking for the upset.
- Oregon State vs. Washington State – A high-octane Pac-12 shootout on tap.
- TCU vs. Texas Tech – A pivotal game for Big 12 standings.
NCAA Football Schedule: Week 4 Matchups, Times & Locations (2025)
Thursday, September 18, 2025
| Matchup | Time (ET) | Location |
|---|---|---|
| Rice @ Charlotte | 5:30 PM | Jerry Richardson Stadium, Charlotte, NC |
Friday, September 19, 2025
| Matchup | Time (ET) | Location |
|---|---|---|
| Tulsa @ Oklahoma State | 5:00 PM | Boone Pickens Stadium, Stillwater, OK |
| Iowa @ Rutgers | 6:00 PM | SHI Stadium, Piscataway, NJ |
Saturday, September 20, 2025
| Matchup | Time (ET) | Location |
|---|---|---|
| Arkansas @ Memphis | TBD | Simmons Bank Liberty Stadium, Memphis, TN |
| Florida @ Miami | TBD | Hard Rock Stadium, Miami Gardens, FL |
| SE Louisiana @ LSU | TBD | Tiger Stadium (LA), Baton Rouge, LA |
| Tulane @ Ole Miss | TBD | Vaught-Hemingway Stadium, Oxford, MS |
| N. Illinois @ Mississippi State | TBD | Davis Wade Stadium, Starkville, MS |
| South Carolina @ Missouri | TBD | Memorial Stadium, Columbia, MO |
| Auburn @ Oklahoma | TBD | Memorial Stadium (Norman, OK), Norman, OK |
| UAB @ Tennessee | TBD | Neyland Stadium, Knoxville, TN |
| Georgia State @ Vanderbilt | TBD | FirstBank Stadium, Nashville, TN |
| Sam Houston @ Texas | TBD | DKR-Texas Memorial Stadium, Austin, TX |
| Oregon State @ Oregon | TBD | Autzen Stadium, Eugene, OR |
| Illinois @ Indiana | TBD | Memorial Stadium (Bloomington, IN), Bloomington, IN |
| Maryland @ Wisconsin | TBD | Camp Randall Stadium, Madison, WI |
| Michigan State @ USC | TBD | Los Angeles Memorial Coliseum, Los Angeles, CA |
| Syracuse @ Clemson | TBD | Memorial Stadium (Clemson, SC), Clemson, SC |
| NC State @ Duke | TBD | Wallace Wade Stadium, Durham, NC |
| Stanford @ Virginia | TBD | Scott Stadium, Charlottesville, VA |
| Kent State @ Florida State | TBD | Doak Campbell Stadium, Tallahassee, FL |
| Temple @ Georgia Tech | TBD | Bobby Dodd Stadium, Atlanta, GA |
| Wofford @ Virginia Tech | TBD | Lane Stadium, Blacksburg, VA |
| SMU @ TCU | TBD | Amon G. Carter Stadium, Fort Worth, TX |
| North Carolina @ UCF | TBD | FBC Mortgage Stadium, Orlando, FL |
| Bowling Green @ Louisville | TBD | L&N Federal Credit Union Stadium, Louisville, KY |
| Arizona State @ Baylor | TBD | McLane Stadium, Waco, TX |
| Wyoming @ Colorado | TBD | Folsom Field, Boulder, CO |
| BYU @ East Carolina | TBD | Dowdy-Ficklen Stadium, Greenville, NC |
| West Virginia @ Kansas | TBD | David Booth Kansas Memorial Stadium, Lawrence, KS |
| Texas Tech @ Utah | TBD | Rice-Eccles Stadium, Salt Lake City, UT |
| Delaware @ FIU | TBD | Pitbull Stadium, Miami, FL |
| Arkansas State @ Kennesaw State | TBD | Fifth Third Stadium, Kennesaw, GA |
| James Madison @ Liberty | TBD | Williams Stadium (VA), Lynchburg, VA |
| Southern Miss @ Louisiana Tech | TBD | Joe Aillet Stadium, Ruston, LA |
| Marshall @ Middle Tennessee | TBD | Johnny “Red” Floyd Stadium, Murfreesboro, TN |
| UL Monroe @ UTEP | TBD | Sun Bowl, El Paso, TX |
| UTSA @ Colorado State | TBD | Canvas Stadium, Fort Collins, CO |
| Fresno State @ Hawai’i | TBD | Clarence T.C. Ching Athletics Complex, Honolulu, HI |
| Idaho @ San José State | TBD | CEFCU Stadium, San Jose, CA |
| UNLV @ Miami (OH) | TBD | Yager Stadium, Oxford, OH |
| McNeese @ Utah State | TBD | Maverik Stadium, Logan, UT |
| Louisiana @ Eastern Michigan | TBD | Rynearson Stadium, Ypsilanti, MI |
| Coastal Carolina @ South Alabama | TBD | Hancock Whitney Stadium, Mobile, AL |
| Troy @ Buffalo | TBD | UB Stadium, Buffalo, NY |
| Toledo @ Western Michigan | TBD | Waldo Stadium, Kalamazoo, MI |
| Duquesne @ Akron | TBD | InfoCision Stadium, Akron, OH |
| Matchup | Time (ET) | Location |
|---|---|---|
| North Texas @ Army | 10:00 AM | Michie Stadium, West Point, NY |
| South Carolina State @ USF | 10:00 AM | Raymond James Stadium, Tampa, FL |
| Wagner @ Central Michigan | 11:00 AM | Kelly/Shorts Stadium, Mount Pleasant, MI |
| Michigan @ Nebraska | 1:30 PM | Memorial Stadium (Lincoln, NE), Lincoln, NE |
| Purdue @ Notre Dame | 1:30 PM | Notre Dame Stadium, Notre Dame, IN |
| Ball State @ UConn | 1:30 PM | Pratt & Whitney Stadium, East Hartford, CT |
| Gardner-Webb @ Ohio | 1:30 PM | Peden Stadium, Athens, OH |
| Murray State @ Jacksonville State | 5:00 PM | AmFirst Stadium, Jacksonville, AL |
| UT Martin @ Missouri State | 5:00 PM | Robert W. Plaster Stadium, Springfield, MO |
| Nevada @ Western Kentucky | 5:00 PM | Houchens Industries–L.T. Smith Stadium, Bowling Green, KY |
| Boise State @ Air Force | 5:00 PM | Falcon Stadium, USAF Academy, CO |
| Maine @ Georgia Southern | 5:00 PM | Allen E. Paulson Stadium, Statesboro, GA |
| Washington @ Washington State | 5:30 PM | Martin Stadium, Pullman, WA |
| Nicholls @ Texas State | 6:00 PM | UFCU Stadium, San Marcos, TX |
| California @ San Diego State | 8:30 PM | Snapdragon Stadium, San Diego, CA |
Expert Betting Picks for Week 4
Best ATS Pick: Oregon State -6.5 vs. Washington State
Oregon State has one of the most balanced attacks in the conference and should control the pace on both sides of the ball.
Moneyline Value: Ole Miss ML vs. Alabama
This might be the week Lane Kiffin gets his revenge. The Rebels are clicking offensively and offer real upset potential.
Top Over/Under: Over 64.5 in TCU vs. Texas Tech
Both teams average 30+ points per game and play with tempo. Expect fireworks.
Player Prop Spotlight: Michigan RB Over 95.5 Rushing Yards
Against a Wisconsin front that’s been leaky this season, Michigan’s ground game could dominate.
Team Prop Watch: Alabama Under 3.5 Touchdowns
With Ole Miss likely to control time of possession and Alabama showing inconsistency, the under offers value.
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What are the biggest games to watch in NCAA Week 4 for 2025?
Michigan vs. Wisconsin and Ole Miss vs. Alabama headline the weekend slate. These are key matchups with playoff and conference title implications.
What types of bets should I look into for Week 4?
Smart bets for Week 4 include spreads (ATS), moneylines, over/unders, and both player and team props. By this point in the season, trends start to stabilize, making props especially valuable.
When is the ideal time to bet during Week 4?
Early in the week for sharp lines, or later in the week if you’re watching injury updates. Monitor line movement daily and stay locked in for value shifts.
Where can I get expert betting advice for Week 4?
SportsHub provides expert picks, stats-driven analysis, and premium service plays across all major betting categories to help you make informed bets for Week 4.