Week 6 NCAA Football Picks

Week 6 NCAA Football Picks

The best thing about the Week 6 NCAA football picks is that it means that October is starting. And, with the start of October, we get Wednesday night college football. What could be better than another day with live college football action? Nothing! That’s why Sports Hub loves college football. That and we get to bring our readers the best analysis, content, and picks in the business.

With the season in Week 6, we’re in full-on conference play mode. Even the Wednesday night doubleheader features a pair of Conference USA matchups – the newest FBS member, Jacksonville State, at Middle Tennessee, and then FIU playing at New Mexico State. We get treated to a Big 12 clash – top-15 Kansas State versus Oklahoma State – and a Big Ten showdown when Nebraska plays at Illinois on Friday night. The big one on Saturday is the Red River Rivalry – Oklahoma and Texas.

Several Top Teams on the Road 

If you’re looking at your Week 6 NCAA football picks, you will notice quite a few AP Top 25 teams playing on the road against unranked opponents. Many of these top teams may win handily, but these games are often known as “trap” games. Higher-ranked teams may be looking ahead to games against other ranked opponents or conference rivals. 

There may be no more significant home-field advantage than that in college football. Most often, all other things being equal, the home team is the favorite in NCAA football. There is a big difference between out-of-conference road underdogs and in-conference road dogs. At this point in the season, we’re into the conference schedule. Keep the following in mind when making your Week 6 NCAA football picks. 

Out-of-conference underdogs that travel 1,000 miles or more to play their opponent win 18.8 percent of the time. In-conference underdogs traveling the same distance win 31.6 percent of the time. The shorter the distance – 200 miles or less – the more in-conference dogs pull the upset. The number moves up to 44.1 percent when the two opponents are closer.

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Our Sports Hub experts have been on their game for six weeks (remember, there was a Week 0) now. They are bringing their expertise once again in Week 6. Remember, many of our elite cappers will offer free Week 6 NCAA football picks. Then, you will also find the best premium service plays in the industry.

There are also Sports Hub computer picks, which started the 2023 season off with a bang. Our computer picks went 20-9 during Week 1, the first whole week of the college football season. An artificial intelligence algorithm generates these picks. The algorithm is heavily based on statistics. Sports Hub computer picks have great value because they are only released when there is a two-point difference between the actual betting line and the computer-derived line. All Sports Hub members have access to these computer picks.

Best Pick ATS

You should always start by looking at spreads when making Week 6 NCAA football picks. The best place to start is in the SEC, as the 5-0 Missouri Tigers are 6.5-point betting underdogs over the 3-2 LSU Tigers.

This line disrespects Missouri based on how things have played out this season, and the Tigers will use that as fuel. Even if LSU can leave the state of Missouri with a win, you should expect to see this game being closer than a 6.5-point spread. 

Missouri Tigers +6.5

Best Moneyline Pick

The Alabama Crimson Tide take on the Texas A&M Aggies on Saturday in a matchup of 4-1 teams in the SEC West Division. This game has instant classic written all over it, as Texas A&M is no stranger to giving Alabama a tough time. 

The Crimson Tide are slim 3.5-point betting favorites in this game, but that offense has struggled to put points on the board. Texas A&M will do what is needed to keep this game close, but taking Alabama to win this game outright is the play to make. 

Alabama Crimson Tide -125

Best Total Pick

Looking at the total number of points in a game is one of the better options when making Week 6 NCAA football picks. The Kentucky Wildcats are set to travel to Georgia to face the Bulldogs, and both teams are a perfect 5-0. 

You should expect a ton of big hitting in this game, and both teams will try to win by getting stops. The point total for this game is set at 48.5 points, but 21 points will be enough to win, and going with the under is the right play. 

Kentucky Wildcats/Georgia Bulldogs Under 48.5

Best Player Prop

The annual Red River Showdown is set to take place this weekend between the Oklahoma Sooners and the Texas Longhorns, and this is always a great game. Texas is a slight favorite in this game, but Oklahoma will try to win in a shootout. 

Oklahoma quarterback Dillon Gabriel is having a monster season, but Quinn Ewers is the best player in this game overall. Look for Ewers to shine for the Texas offense, as the Longhorns will get the job done. 

Quinn Ewers Over 2.5 TD Passes

Best Team Prop

The Arkansas Razorbacks will take on the Ole Miss Rebels in Week 6, and the home team is a big 10.5-point betting favorite. Ole Miss scored 55 points in a win over the LSU Tigers, and that offense is clicking on all cylinders. 

It’s been a rough season for the Razorbacks up to this point, and that defense will be tested significantly in this one. Look for Ole Miss to have another considerable offense day, as they will find the end zone at least five times. 

Ole Miss Rebels Over 4.5 Team Touchdowns

Notre Dame Fighting Irish vs. Louisville Cardinals

The 5-0 Louisville Cardinals try to stay undefeated when they host the Notre Dame Fighting Irish, and this will be a challenging test. Louisville has shown the ability to score some points this year, but the Notre Dame defense is terrific. 

The Fighting Irish also come into this game with some momentum after beating the Duke Blue Devils, which will matter. Notre Dame will take control of this game, and they will win it by double-digits. 

Notre Dame Fighting Irish -6.5

Marshall Thundering Herd vs. NC State Wolfpack

The 4-0 Marshall Thundering Herd are heading into the ACC to face the NC State Wolfpack on Saturday in what should be a great game. NC State is a six-point betting favorite in this one, but they have also struggled at times. 

Marshall will be desperate to remain undefeated this season, and they will do everything in their power to pick up a win. NC State will come up with a win, but taking the points is the best bet in this one. 

Notre Dame FightingMarshall Thundering Herd +6.0 Irish -6.5

Central Michigan Chippewas vs. Buffalo Bulls

The action in the Mid-American Conference (MAC) is starting to heat up, and that will only continue as the year progresses. Central Michigan travels to Buffalo on Saturday, and the spread in this game is just 2.5 points. 

Buffalo has struggled to win games this season, as they have won just once, and they are facing a Central Michigan team that can score. Things won’t be easy for the Chippewas in this matchup, but taking them on the money line at -115 is the way to go.

Central Michigan Chippewas -115

Syracuse Orange vs. North Carolina Tar Heels

The race in the ACC continues to be wide open, although it seems every team is trying to track down the Florida State Seminoles. North Carolina has a chance to win this conference, but they must deal with the 4-1 Syracuse Orange on Saturday. 

Syracuse has an offense that can strike in a hurry, and they are also a team that can be extremely physical on both sides of the ball. That will matter in this game as the Orange will find a way to keep it close, but North Carolina wins. 

Syracuse Orange +9.0

Texas State Bobcats vs. Louisiana Ragin’ Cajuns

The Sun Belt Conference always seems to produce some exciting games, and Texas State and Louisiana will try to continue that tradition on Saturday. Texas State is a slim one-point betting favorite on the road, and they do come into this game with a better record. 

The Bobcats nearly blew a massive lead in Week 5, which will matter when making Week 6 NCAA football picks. Playing at home will give Louisiana a big boost, and they will make just enough plays to win this game.

Louisiana Ragin’ Cajuns +110

Make the Most of Week 6 NCAA Football Picks 

The conference schedules continue. The best teams in the nation will all be in action. Is this the week where one of the country’s best teams takes a fall? The big one on Saturday features a Texas team with a massive win over Alabama this year. The winner may have the inside track at earning a shot in the Big 12 championship game.

Whether it’s Sooners-Longhorns or another big Week 6 conference matchup, stay with us here at Sports Hub. We’ve got the best Week 6 NCAA football picks, the best analysis, and the best content to prepare you for another college football weekend. You can get plenty of information at Sports Hub. If you become a member, you can get even more! Guidelines on how to strategically place wagers on football matches.

Elevate Your Game with Our Week 6 NCAA Picks

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Week 6 NCAA Football Picks FAQs

What is a successful college football betting strategy I can use?

One of the most straightforward and basic betting strategies that college football bettors can use is proper money management. With your Week 6 NCAA football picks, determine which bets you will place. Then, use our betting unit size strategy to make your wagers. Professional bettors typically use a scale and bet accordingly. If it’s a bet they are confident in, they will bet their maximum unit size. If they like the chance but don’t have the same confidence, they will bet a half unit or maybe even a quarter unit. 

What are the key numbers for betting college football totals?

More college football games end with a total combined score of 55 than any other number. Next on the list are 51 and 41. Totals of 59 and 58 round out the top 5. Those five numbers have accounted for over 15 percent of all final scores in college football since 2017. Knowing these key numbers can help bettors make decisions on NCAAF total bets.

How do I identify the CFB favorite on the money line? 

If you’re making your Week 6 NCAA football picks, you can quickly identify the money line favorite in a college football game. The money line choice for a college football game is determined by its unfavorable odds. In the following example, Penn State is a -830 favorite over Illinois. On the other side of the bet, Illinois is a +550 underdog. 

Penn State -830
Illinois +550